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High-Throughput Image Reconstruction and Analysis (Bioinformatics & Biomedical Imaging) ReviewAre you interested in the emerging challenges of microscopy? If you are, then this book is for you! Editors A. Ravishankar Rao and Guillermo A. Cecchi, have done an outstanding job of editing contributed book chapters from authors (that are experts in their fields), that explore how the coupling of high-throughput computing (HPC) with automated imaging techniques, can impact and further our understanding of complex biological systems.The book begins with an examination of new technologies to investigate biological systems. Next, it takes a closer look at how computations can be parallelized. Then, the book examines specific applications of parallel computing to solve biological imaging problems. Finally, it describes what happens after the microscopic images have been acquired and analyzed; and, the need for the images to be stored in databases that facilitate their retrieval for processing.
This most excellent book presents a state-of-the-art survey of leading edge microscopy techniques, and the upcoming challenges they face. More importantly, this book familiarizes readers with game changing techniques in bio-imaging, analyzes the impact they will have, and provides recommendations on how to best harness this emerging technology.High-Throughput Image Reconstruction and Analysis (Bioinformatics & Biomedical Imaging) OverviewToday's bioimaging technologies generate mountains of biological data that can simply overwhelm conventional analysis methods. This groundbreaking book helps researchers blast through the computational bottleneck with high-performance computing (HPC) techniques that are blazing the way to never-before bioimaging, image analysis, and data mining capabilities and revolutionizing the study of cellular and organ-level systems. This innovative volume surveys the latest advances in scanning electron microscopy, knife-edge scanning microscopy, and 4D imaging of multi-component biological systems. The book includes detailed case studies that show how key techniques have been successfully deployed in medical image analysis, drug discovery, tissue analysis, functional MRI data analysis, and other areas.
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